The Axanthic condition is defined as the lack of yellow and orange pigments in the skin, this mutation has also been exhibited in royal pythons. An axanthic Kenyan sand boa looks like a black-and-white photograph of a normal specimen, and in the same way axanthicism in royal pythons has proven to be inheritable, axanthicism in Kenyan sand boas has also proved simple recessive.

The axanthic lineage of the Kenyan sand boa ‘popped up’ serendipitously in the same year in both the collections of Lloyd Lempke and Bean Farm. So far as we know, there has never been a wild-caught axanthic Kenyan sand boa.